Japan-Flag Korea-Flag China-Simplified-Flag China-Traditional-Flag  

Premier Sponsors:  

Beckman Coulter Life Sciences 

Boston Healthcare


Charles River Discovery




Silicon Biosystems   




  View All Sponsors 

Archived Content

Bioinformatics Cancerinformatics 

View Program Video  

Bioinformatics & Cancer Informatics Promo Video 

Day 1 | Day 2Day 3 | Download Brochure 

Explosive growth of biological information has resulted from many advances in the field of molecular biology and sophisticated techniques and equipment used to carry out rapid genome sequencing. These advances have enabled improvement in biological research and clinical medicine. For example, scientists are able to find cures for some hereditary or acquired diseases and cancers by viewing or analyzing genes directly related to them. Through the use of computational tools and methods, scientists can observe the molecular basis of a disease. Drugs can then be designed that target those genes which are diseased.

With the ever-increasing volume of information generated for curing or treating diseases and cancers, computer-based storage, processing, and dissemination is needed to turn this data deluge into meaningful biological knowledge. Leading experts from industry, government, and healthcare organizations will present compelling talks and best practice examples on annotation, storage, analysis, and search/retrieval of nucleic acid sequence, protein sequence, and structural information. Lectures and panel discussions will be framed around content, analysis software and services, IT infrastructure and other services.


Tuesday, February 21

7:00 am Registration


Plenary Keynote SESSION  

8:00 Plenary Keynote Presentations  

  Sponsored by
Hologic Molecular Diagnostics - small logo 

9:40 Grand Opening Refreshment Break in the Exhibit Hall with Poster Viewing



11:00 Chairperson’s Opening RemarksKevin Davies, Ph.D., Editor-in-Chief, Bio-IT World 


11:10 Data Liquidity: The Holy Grail at our Fingertips 

Ken Buetow, Ph.D., former Director, Center for Biomedical Informatics and Information Technology, National Cancer Institute

Technical and cultural barriers to seamless data exchange for cancer and other disease research are now surmountable through new models that encompass all stakeholders. This presentation highlights precompetitive development and usage of digital frameworks designed to connect innovators through open interfaces between digital systems.

11:40 Analyzing Biomedical Text Towards Building Multi-faceted Nutrigenomics Networks

Hui Yang, Ph.D., Assistant Professor, Department of Computer Science, Center for Computing for Life Sciences (CCLS), San Francisco State UniversityAdvances in bio-technology and life sciences are leading to an ever-increasing volume of published research data, predominantly in unstructured text. To uncover the underlying knowledge base hidden in such data, text mining techniques have been utilized. Past and current efforts in this area have been largely focusing on recognizing gene and protein names, and identifying binary relationships among genes or proteins. In this talk, I will present an information extraction system currently under development at San Francisco State University. This system analyzes scientific publications in an emerging discipline--Nutritional Genomics, a discipline that studies the interactions amongst genes, foods and diseases--aiming to automatically construct nutritional genomics (or nutrigenomics) networks that capture the aforementioned interactions.  We are especially interested in the health benefits of foods and their nutrients and their impact over different diseases. We expect such networks will benefit both health
professionals and the general public.    

12:10 pm  Oncology Pharmacogenomics Data Integration and Beyond: Right Information and Smart Information  

Lihua Yu, Ph.D., Director of Bioinformatics, H3 Biomedicine, Inc.

AstraZeneca’s cancer pharmacogenomics data integration systems manage multi-dimensional data from compound profiling to cell line and in vivo model molecular profiling. Learn the system’s key functionalities, its application to drug discovery and translational science projects, and how crowd intelligence is changing its information delivery.

 12:40 Luncheon Presentation I
Integrated Biobanking - Specimen Management from an Institutional Perspective
Sponsored byBiofortis smaller
Steve Chen, Director of Marketing, BioFortis, Inc.
Most biobanks today use stand-alone biobanking software to address the operational aspects of their biospecimen collections. As a result, additional IT resources are needed if researchers want to tie-in data repositories that contain clinical, molecular, and other types of information about those samples. In this presentation, we describe how an "integrated biobanking" approach can better support biospecimen management and drive scientific discovery from an enterprise, multi-group, multi-study perspective.

Sponsored byReveLytix
1:10 Luncheon Presentation II
Integrating R&D Data in a Highly Distributed Data Environment
Todd Jones, Sr. Information Architect, Spry
Mike Lang Jr., VP, Director of Ontology Engineering Services, Revelytix 
This topic presents a system for enabling arbitrary analysis across distributed data sources using W3C semantic standards. It shows how the pharma industry can leverage this system for data validation and integration, policy compliance enforcement, and inferencing.

1:45 Dessert in the Exhibit Hall with Poster Viewing 


2:15 Chairperson’s Remarks

Carol Hill, Ph.D., Informatics Project Leader II, Clinical Data Integration, Duke Clinical Research Institute

2:20 Creating Informatics Tools and an Organizational Support Paradigm to Facilitate Bi-Directional Translational Research

Paul A. Harris, Ph.D., Director, Office of Research Informatics Operations; Associate Professor, Biomedical Informatics & Biomedical Engineering, Vanderbilt University

Data collection and integration is essential for clinical and translational research.  This presentation will highlight informatics-centered tools leveraging secondary use of clinical data.  Topics will include research data warehousing, biorepository integration, participant recruitment and semi-automated population of project research databases.

2:50 Secondary Use of Healthcare Data for the Study of Genomics and Pharmacology

Shawn Murphy, M.D., Ph.D., Associate Professor of Neurology, Research IT, Partners HealthCare

Informatics for Integrating Biology and the Bedside (i2b2) is a project now installed at over 60 hospitals to provide clinical investigators with the software tools necessary to integrate medical record and clinical research data in the genomics age.   Patient medical record data, including diagnoses, medications, laboratory values, and outcome variables can be combined with clinical research and molecular data into a single cohesive unit.   The generic data model and the service oriented architecture of i2b2 lends itself to a natural implementation of a distributed query system among the hospitals.

3:20 Clinical Research Informatics:  Challenges and Opportunities in Translational Research

Carol Hill, Ph.D., Informatics Project Leader II, Clinical Data Integration, Duke Clinical Research Institute

Clinical Research Translational Informatics interfaces exploratory and clinical efforts.  Integration across clinical/hospital/research boundaries requires contextual understanding.  I will discuss efforts and challenges in developing backend standards, defining data sets (Meta-Metadata tool), and developing cross-project infrastructure for biomarker research.

Sponsored by

3:50 Aggregating & Harmonizing Disparate Data Sources: The Key to Pattern Recognition

Gary Kennedy, Chairman & CEO, RemedyMD

Sponsored by 
Complete Genomics 

4:05 Breaking the Mold:  Whole Genome Sequencing as a Diagnostic Assay

Jill Hagenkord,MD Chief Medical Officer, Complete Genomics

Whole genome sequencing is enabling researchers to identify novel disease-causing variants and to assess multiple pathways in a single assay. This presentation reviews cases of clinical utility, near-term applications.

4:20 Reception in the Exhibit Hall (Sponsorship Available)

5:20 Breakout Discussions in the Exhibit Hall

Concurrent problem solving breakout discussions, open to all attendees, speakers, sponsors, and exhibitors, provide a forum for discussing key issues and meeting potential collaborators. Plan to take part and explore these topics in-depth. Please pick a topic of your choice, find your table and join in.

Transcription Factors

Moderator: Stuart Tugendreich, Product Management Director - IPA, Ingenuity Systems

  • * TF binding prediction vs. ChIP-Seq and other experimental approaches
  • * Post translational regulation of TFs and feedback loops
  • * TF cascades
  • * TFs as drug targets

Bridging the Gaps in Translational Informatics

Moderator: Jonathan Usuka, Ph.D., M.B.A., Director, Global Business Partnering, Celgene Corporation

  • * The $1000 Genome in the $100 Million Clinical Trial
  • * Do Novel Targets still matter? Pathway Analysis comes of age
    * What do we know and when do we know it? Integrating biomarker and clinical data for Go/No-Go decisions
    * Three vital acronyms for 21st Century drug discovery: LIMS, ELNs and CROs

    Causal vs Correlative Diagnostics and Biomarkers: Understanding the Difference
    Moderators: Michael Liebman, Ph.D., Managing Director, Strategic Medicine, Inc. and
    Sabrina Molinaro, Ph.D., Institute for Clinical Physiology, National Research Council, Italy

    * Understanding the limitations of correlation and the opportunity for causality
    * Analyzing and evaluating existing algorithms for risk and diagnosis
    * The need to address biological complexity and process to the equation

6:20 Close of Day

Day 1 | Day 2Day 3 | Download Brochure