Integrated R&D Informatics and Knowledge Management
Leveraging IT and Informatics to Enable Global Information Sharing
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As the world of drug discovery gets smaller, and companies become more dependent on collaborations and outsourcing to move forward, the line separating IT from researchers is harder to see. It is crucial for sites to find global enterprise solutions to enable data integration and information sharing within and across internal and external departments. Integrated R&D Informatics and Knowledge Management will highlight strategic infrastructures being put in place to facilitate knowledge sharing and collaborations, including novel approaches to work with data from external and public sources, leverage data from multiple internal sources, establish an effective bioregistry, manage sequencing data, and support complex clinical candidates like ADCs.
Wednesday, February 13
7:00 am Registration and Morning Coffee
8:00 – 9:40 am Plenary Keynote Presentation - Personalized Oncology – Fulfilling the Promise for Today's Patients
In honor of the 20th anniversary of the Molecular Medicine Tri-Conference, CHI and Cancer Commons will present a plenary panel on Personalized Oncology. Innovations such as NGS and The Cancer Genome Atlas have revealed that cancer comprises hundreds of distinct molecular diseases. Early clinical successes with targeted therapies suggest that cancer might one day be managed as a chronic disease using an evolving cocktail of drugs.Representing all five conference channels, Diagnostics, Therapeutics, Clinical, Informatics, and Cancer, a panel of experts will lead a highly interactive exploration of what it will take to realize this vision in the near future.
9:40 Refreshment Break in the Exhibit Hall with Poster Viewing
11:00 Chairperson's Opening Remarks
Manish Muzumdar, Senior Vice President, Products, Remedy Informatics
11:10 Internal Collaboration
Arturo Morales, Ph.D., Global Leader Data Federation Initiative, Informatics Systems Lead, Novartis
The Novartis Data Federation Initiative aims to enable global project teams by providing a seamless collaborative environment that integrates data, information and knowledge generated within and outside NIBR.
11:40 Technology for Collaborative Development of Ontologies for Data Analysis and Integration
Mark A. Musen, M.D., Ph.D., Professor of Medicine, Biomedical Informatics, Stanford Center for Biomedical Informatics Research
Work with "big data" requires well-defined ontologies for annotation, retrieval, integration, and analysis.The National Center for Biomedical Ontology is developing a comprehensive infrastructure to support collaborative authoring, dissemination, open peer review, and use of ontologies over the Web.
12:10 pm Pre-Competitive Collaboration
Sandor Szalma, Head, External Innovation, R&D IT at Janssen Research & Development, LLC
To increase innovation in non-core areas, pharma companies have recently been more open to establish precompetitive partnerships. Several successful examples have been emerging such as the EU Innovative Medicines Initiative, the Pistoia Alliance and most recently TransCelerate BioPharma. In this presentation we discuss several improved outcomes from such informatics and IT collaborations.
12:40 Luncheon Presentation I: Liberating the
Knowledge in your Biospecimens through Next Generation Biobanking
Mark A Collins, Ph.D., Director, Marketing, BioFortis, Inc.
Traditional biobanking software is sample-centric. However, Next Generation Biobanking software extends support into biomarker-based clinical research carried out in a distributed ecosystem of vendors, partners and collaborators, while ensuring security and compliance. Next Generation Biobanking case studies will be presented
1:10 Luncheon Presentation II: Better End-User Analysis and Decision Making by Considering All Data from Anywhere
Lee Feigenbaum, Vice President, Marketing & Technology, Cambridge Semantics
The increasing availability of diverse information critical to pharmas’ success challenges end users to effectively find, understand, and share any data from anywhere. Pharmas are deploying Unified Information Access solutions based on semantic technology to answer this challenge in areas such as Competitive Intelligence and Pharmacovigilance. This talk will showcase new capabilities and value these solutions are giving users today.
1:45 20th Anniversary Cake in the Exhibit Hall with Poster Viewing
2:15 Chairperson's Remarks: The De-Evolution of Informatics: How Externalization is Radically Changing the Informatics Landscape
Mike Elliott, Ph.D., CEO, Atrium Research & Consulting LLC
The rush toward externalization is transforming traditional approaches to informatics architectures.Increasing business development activity is forcing IT to confront new questions and to modify existing architectures. This session will discuss this trend and how organizations are addressing the challenges.
2:20 Fully Integrated Pharmaceutical Network (FIPnet): AstraZeneca R&D Case Study
Arun Nayar, Global Head, External Collaborations, R&D, Information, AstraZeneca Pharmaceuticals
We will share our experiences in deploying Informatics platforms to enable externalization and virtualization of key R&D capabilities in support of Virtual NeuroScience Innovative Medicine and other R&D functions.
2:50 Externalization as a Platform to Enable Integrated Collaboration: A Merck R&D Case Study
Phyllis Post, Executive Director, Merck & Co., Inc.
Merck R&D has implemented an integrated partner portal that is designed to enable consolidated collaboration with our strategic partners—ranging from academic institutions to investigators to CRO's and more. The objective is for the Partner Portal to provide a user-centric "window to the world" for our partners to collaborate and interact with Merck R&D in an efficient, agile and effective manner.
3:20 PANEL DISCUSSION: Measuring and Showing the Impact of IT and Informatics on Collaboration
Moderator: Martin Leach, Ph.D., Vice President, Research & Development IT, Biogen Idec
Mike Elliott, Ph.D., CEO, Atrium Research & Consulting LLC
HongMei Huang, Ph.D., Director and Site Head, NIBR IT Emeryville, Novartis
Joseph F. Donahue, Senior Vice President, Intellectual Property & Science, Thomson Reuters
3:50 Searchability and Findability in the Brave New World of Big Data
Andreas Matern, Vice President, Disruptive Innovation, Thomson Reuters
The data deluge has made the 'findability' of information a priority, especially in the life sciences. This talk will discuss some of the trends in the industry around not just searching for meaningful data, but more importantly, finding answers to questions.
4:20 Networking Reception in the Exhibit Hall with Poster Viewing (Sponsorship Opportunities Available)
5:20 Breakout Discussions in the Exhibit Hall
Moderated by: Mary Bradley, Ph.D. M.B.A., CollaborationFinder
- Building a Global Enterprise – Integrating Data from Smaller Sites into Larger Sites
- Integration of Data from Recently Purchased Companies (standardization etc.)
- Precompetitive – Pharma to Pharma
Moderated by: Mike Elliott, Ph.D., CEO, Atrium Research & Consulting LLC
- Enabling Data Sharing Globally Across Time Zones, Company Sites outside US and with External Collaborators (CROs)
- Management tools for external collaboration
- Managing Data Flow on Outsourcing
- Collaboration Pharma to Academic or Government
- Collaborating with biotech and pharma on clinical trials – clinical centers
Moderated by: Carol Bova Hill, Ph.D., Informatics Project Leader II, Clinical Research Informatics, Duke Clinical Research Institute
- Collaborations strategies between Biotech/Pharma/Insurance companies/Academic/Medical Centers
- Where is the value chain? Approaches to fund translational research.
- Boundaries between medical practice, human research and discovery research – data flow, standards, regulations
- Decision support & emerging technologies/trends – what is hot, what is not
6:20 Close of Day
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