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2013 Archived Content

Digital Pathology

Defining a New Standard


Day 1 | Day 2 | Day 3 | View TRICON Attendees 

Digital pathology involves the management and interpretation of pathology information in a digital environment that enables a collaborative approach to patient care and research. The field is gaining global acceptance in the medical and research community. Continued benefits and applications of digital pathology images will ensure the rapid adoption of digital pathology in mainstream use. This conference addresses all aspects of digital pathology related to the imaging process, as well as current and emerging applications. Expert speakers will cover topics related to imaging workflow, uses in clinical practice, telepathology, image analysis, regulatory issues, and advanced imaging tools.

Scientific Advisory Board

Kenneth J. Bloom, M.D., Chief Medical Officer, Clarient Inc
Eric F. Glassy, M.D., Medical Director, Pathology, Inc.
Liron Pantanowitz, M.D., Associate Professor of Pathology, University of Pittsburgh Medical Center; Department of Pathology, UPMC Shadyside

Here are just some of the leading organizations that are attending Digital Pathology. Should your company be on this list?

AG Mednet
Agilent Technologies Inc.
Arizona State University
BC Cancer Agcy
Bio Rad Labs Clinical Diagnostics Group    
Biogen Idec Inc.
BioTree Systems
California Institute of Technology
Canterbury District Heath Board
Canterbury Health Labs
Cell Signaling Technology
Celligent Diagnostics
Childrens Hospital Los Angeles
College of American Pathologists
Cornell University
Digital Science
Eli Lilly & Co.
EMC Isilon Storage Division
GE Healthcare
Genomic Health Inc.
Harvard Medical School
James A Haley Veterans Hospital
LigoLab Inc.
Lumiphore Inc.
Massachusetts General Hospital
Medical College of Wisconsin
Merrimack Pharmaceuticals
Millennium The Takeda Oncology Company
Momenta Pharmaceuticals Inc.
Parker Hannifin
Pathology Inc.
Philips Medical Systems
Philips Research
Queens University of Belfast
Roche Diagnostics - Ventana Medical Systems
Siemens Corp Research
Siemens Healthcare Diagnostics
Sunquest Information Systems
Toronto General Hospital
Ultralight Histology
UNeMed Corp.
University of Arizona
University of California Davis
University of California Los Angeles
University of California San Francisco
University of California Santa Barbara
University of Illinois Chicago
University of Kentucky
University of Michigan
University of New South Wales
University of Oklahoma
University of Pittsburgh
University of Rochester
Ventana Medical Systems
Yale University
Yuma Regional Medical Center 



Wednesday, February 13

7:00 am Registration and Morning Coffee


Plenary Keynote Session 

8:00 – 9:40 am Plenary Keynote Presentation - Personalized Oncology – Fulfilling the Promise for Today's Patients

In honor of the 20th anniversary of the Molecular Medicine Tri-Conference, CHI and Cancer Commons will present a plenary panel on Personalized Oncology. Innovations such as NGS and The Cancer Genome Atlas have revealed that cancer comprises hundreds of distinct molecular diseases. Early clinical successes with targeted therapies suggest that cancer might one day be managed as a chronic disease using an evolving cocktail of drugs.Representing all five conference channels, Diagnostics, Therapeutics, Clinical, Informatics, and Cancer, a panel of experts will lead a highly interactive exploration of what it will take to realize this vision in the near future.

Read more 

9:40 Refreshment Break in the Exhibit Hall with Poster Viewing



11:00 Chairperson's Opening Remarks

Eric F. Glassy, M.D., Medical Director, Pathology, Inc.

11:10 Digital Pathology: The Big Picture

Liron Pantanowitz, M.D., Associate Professor of Pathology, University of Pittsburgh Medical Center; Department of Pathology, UPMC Shadyside

Digital imaging is a disruptive technology undergoing widespread adoption in Pathology. Digital images are increasingly being used to make diagnoses, carry out telepathology, perform image analysis, assist with quality assurance, education, and research and often employed for business purposes. Pathology digital images are also becoming more integrated with information systems, imaging standards are evolving, and new regulatory issues are arising. This talk provides an overview of all key aspects of the emerging field of Digital Pathology.

Image Analysis & Advanced Imaging 

11:40 Workflow Management: From Imaging to Analysis and Database Curation

BS Manjunath, Director, Center for Bio-image Informatics; Vice Chair and Undergraduate Program Director, Department of Electrical and Computer Engineering, University of California Santa Barbara

12:10 pm Multiplexed Imaging, Pathology and Personalized Medicine: Keeping Sight of the Forest

Richard Levenson, M.D., Professor and Vice Chair for Strategic Technologies, Department of Pathology & Laboratory Medicine, University of California Davis Medical Center

Molecular analysis has revealed immense complexity in cancer genomes and expression profiles, critical aspects of which can be captured using spatially resolved, multiplexed molecular techniques now available to research and clinical pathology communities. However, tumor-centric complexity should not overshadow the critical roles that the host (stromal) compartments play in determining treatment response and ultimate outcomes.

12:40 Luncheon Presentations (Sponsorship Opportunities Available) or Lunch on Your Own

1:45 20th Anniversary Cake in the Exhibit Hall with Poster Viewing

2:20 Ephemeral Images, Indelible Data: The Promises and Challenges of Digital Imaging as Applied to Pathology

Ulysses Balis, M.D., Ph.D., Associate Professor, Pathology, University of Michigan

Pathology, as a diagnostic specialty, is well along in its adoption and use of digital images for routine clinical workflow, research and education.  However, with an anticipated deluge of image-based data, combined with the reality that many scientists within the collective domains of pathology and its affiliated life sciences specialties are largely unprepared to manage the gargantuan datasets intrinsic to such digital repositories, there emerges a challenge to make best use of this data, besides simply viewing it.  This presentation will highlight several promising areas of digital image algorithm development that can help to span the divide between life scientist and imaging informaticist, with a focus on actual discovery and workflow models.  Live demonstrations of image analysis and image search  software will be included.

2:50 Filling the Training Gap for Future Pathologists: How Does a Novice like Me Catch Up?

Lewis A. Hassell, M.D., Department of Pathology, University of Oklahoma College of Medicine

This session will focus on the learning models and methods appropriate to bringing on line sophisticated image analysis tools, with particular reference to differences between early and late adopters, as well as laboratory validation and credentialing issues that may be raised by these new technologies. Generational differences in learners will also be addressed.

3:20 Q&A with Speakers


Definiens3:50 Accelerating and Advancing Dx and CDx Biomarker Development from Discovery to Clinical Trials by Seamlessly Integrating Image Analysis with Data Mining

Alan Jerusalmi, Ph.D., Director, Professional Services, Definiens

Automating the analysis of histological slides for biomarker development supports comprehensive biomarker expression profiling and morphological fingerprinting in unsurpassed detail and accuracy. Workflow automation and highly efficient data correlation, predictive modeling and validation reduce study length from weeks to days.

4:20 Networking Reception in the Exhibit Hall with Poster Viewing (Sponsorship Opportunities Available)

5:20 Breakout Discussions in the Exhibit Hall

ePathology Solutions

Moderator: Eric F. Glassy, M.D., Medical Director, Pathology, Inc.

   • What are the key drivers of epathology adoption?
   • What are the main barriers to epathology adoption?
   • Regulatory issues and validation issues
   • What are the game-changing apps for epathology?
   • What are the success stories of early adopters?

Involving Academic Pathologists and Clinical Labs while Developing Companion Diagnostics for Industry

Moderator: Steven Potts, Ph.D., CEO, Flagship Biosciences

Integrating Pathology Images and Information Systems

Moderator:  Liron Pantanowitz, M.D., Associate Professor of Pathology, University of Pittsburgh Medical Center; Department of Pathology, UPMC Shadyside

   • Why is there a need for the LIS to become a PACS?
   • Is it better to use an LIS integrated or separate image management system?
   • What will it take for digital images to drive the workflow?
   • Should we share our pathology images with clinicians in the EMR?

A Systems Approach to Pathology

Moderator: Sylvia L. Asa, M.D., Ph.D., Medical Director, Laboratory Medicine Program, University Health Network and Lakeridge Health; Senior Scientist, Ontario Cancer Institute; Professor, Department of Laboratory Medicine & Pathobiology, University of Toronto

Multiplexed Imaging, Pathology and Personalized Medicine

Moderator: Richard Levenson, M.D., Professor and Vice Chair for Strategic Technologies, Department of Pathology & Laboratory Medicine, University of California Davis Medical Center

   • Implications of tumor heterogeneity for multiplexed marker detection strategies--what to do with the answers?
   • How do metabolomic and tumor immunotherapy approaches affect choice of markers to image?
   • And what about the stroma?

Next Generation Approaches to Cellular Analysis

Moderator: Kenneth J. Bloom, M.D., Chief Medical Officer, Clarient, Inc.

6:20 Close of Day

Day 1 | Day 2 | Day 3