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2014 Archived Content

Cambridge Healthtech Institute’s Second Annual

Digital Pathology

Transforming Medicine in a Digital World

February 10-12, 2014 | Moscone North Convention Center | San Francisco, CA


The field of pathology is being reshaped by advances in digital imaging and information sharing. The shortage of pathologists overseas can be addressed by digital pathology, and will also enable the integration of molecular technologies as part of the diagnosis. Important developments such as the concern around validation of digital image analysis and the adoption for primary diagnosis in Canada will be reviewed. Additional factors influencing the uptake of digital pathology will be addressed, such as the increasing prevalence of mobile health platforms and telemedicine, the demand for patients to have access to their information, and the need for pathology expertise abroad.


MMTC Digital Path gif 



Day 1 | Day 2 | Day 3 | Download Brochure 

Monday, February 10

Scientific Advisory Board

Kenneth J. Bloom, M.D., Chief Medical Officer, Clarient Inc
Eric F. Glassy, M.D., Medical Director, Pathology Inc
Liron Pantanowitz, M.D., Associate Professor of Pathology, University of Pittsburgh Medical Center; Department of Pathology, UPMC Shadyside
David L. Rimm, M.D., Ph.D., Professor, Pathology, Yale University

10:30 am Conference Program Registration


11:50 Chairperson’s Opening Remarks

Ralf Huss, M.D., Chief Medical Officer, Definiens AG

12:05 pm American Telemedicine Association (ATA) Updated Guideline on Telepathology

Liron Pantanowitz, M.D., Associate Professor, Pathology, University of Pittsburgh Medical Center

The practice of telepathology has evolved significantly. New technology has been developed, clinical and non-clinical applications have expanded, innovative business opportunities have arisen, and regulatory issues have emerged. The ATA accordingly convened a working group to develop updated guidelines to address these trends. This talk will review these new guidelines addressing issues regarding technology, clinical practice, applications, clinical and facility responsibilities, validation, training, reporting, quality assurance, maintenance, and security, as well as medicolegal, regulatory and ethical considerations.

12:35 Pushing the Resolution Limit with a Simple LED Array

Guoan Zheng, Ph.D., Assistant Professor, Biomedical Engineering & Electrical Engineering, University of Connecticut

Conventional slide scanner acquires multiple high-resolution images and stitches them in the spatial domain. We discuss an imaging modality, termed Fourier ptychographic microscopy (FPM), which acquires multiple low-resolution images and stitches them in the Fourier domain. We report a FPM prototype that uses a LED array and a 2X objective lens to achieve the resolution of a 20X objective lens.

1:05 Session Break

1:15 Luncheon Presentation I: Pathology - From an Analog Art to a Digital Science

Ralf Huss, M.D., Chief Medical Officer, Definiens AG

Anatomical pathology has been evolving from a merely descriptive (analog) subject of post-mortem autopsies to a single cell-based analysis of molecular events that might even predict the response to targeted therapies. Now, tissue-based diagnostics reaches the next level of clinical utility with the quantitation of almost endless (big) data points and context-based digital information, mining all available sets of information from individual samples, including the clinical outcome, and translating it into "Tissue Phenomics."

1:15 Luncheon Presentation II (Sponsorship Opportunity Available)  

2:15 Session Break


2:30 Chairperson’s Remarks

Eric F. Glassy, M.D., Medical Director, Pathology, Inc.

2:35 IVM Diagnosis in Surgical Pathology: Present and Future

Maria M. Shevchuk, M.D., Anatomic Pathology & Clinical Pathology, Weill Cornell Medical College

In vivo microscopy technologies are used as in vivo intraprocedural diagnostic tools, and for ex vivo applications in the surgical pathology. In the near future, these technologies will become an integral part of the practice of pathology. This lecture highlights the current uses, and addresses several “value added” applications for the future. The participants will be better able to introduce these technologies into their practice of surgical pathology.

3:05 In vivo Microscopy: Technologies, Applications and Roles for Pathologists

Guillermo J. Tearney, M.D., Ph.D., Mike & Sue Hazard Family MGH Research Scholar, Professor, Pathology, Harvard Medical School; Wellman Center for Photomedicine, Massachusetts General Hospital

3:35 In vivo Imaging of Cell and Tissue Dynamics: Towards Biologically Relevant Diagnostic Models in Surgical Pathology

Kamran Badizadegan, M.D., FCAP, Chair, Pathology & Laboratory Medicine, Nemours Children’s Hospital; Professor of Pathology, UCF College of Medicine

Surgical pathology, considered the gold standard in anatomical diagnosis, is by and large a subjective pattern recognition exercise in which excised, chemically fixed, thinly sectioned and stained tissues are examined by a bright field light microscope. Although this practice has served medicine well for decades, it ignores the dynamical cell and tissue processes that define health and disease. This presentation will build on the general concept of in vivo microscopy (IVM) to make a case for cell and tissue dynamics as potential diagnostic criteria.


4:05 An Objective Image Quality Model Based on Subjective Pathology Perception Test

Dirk Vossen, Ph.D., Philips Digital Pathology

4:35 Refreshment Break and Transition to Plenary Keynote

5:00 Plenary Keynote Session (Click Here For More Details)  

6:15 Grand Opening Reception in the Exhibit Hall with Poster Viewing

7:45 Close of Day

Day 1 | Day 2 | Day 3 | Download Brochure