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Archived Content

Translational Science 

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Thursday, February 23



8:30 am Chairperson's Remarks

Patricia McDonald, Ph.D., Associate Scientific Director, Translational Research, The Scripps Research Institute

8:35 Translational Research at Scripps Florida

Patrick Griffin, Ph.D., Director, Translational Research, The Scripps Research Institute

Discussion focused on the Scripps National Screening Center, as well as the successful collaborations in translational research with pharmaceutical partners; examples from Eli Lilly and Pfizer.

9:05 Translating Innovation into Personalized Medicine: A Centralized Approach for Fostering Research and Engaging Physicians in a Large National Community Hospital Network

Jeffrey M. Otto, Ph.D.,  M.B.A., National Director, Catholic Health Initiative's Center for Translational Research

Research partnerships leverage the CTR's CLIA MDx laboratory, biospecimen procurement / repository, healthcare data analytics, and research capabilities to develop improved tools for physicians in the community hospital setting.

9:35 Driving Innovation with Forward and Reverse Translation in the Academic Setting

Virginia Burns, Ph.D., Associate Director, Technology Resources, Duke Translational Medicine Institute,  Duke University

Sponsored by

10:05 Plasma-Based Biomarkers in the Preclinical and Clinical Development of Novel Human ImmunomodulatorsRobert Hershberg, MD, Ph.D., President and Chief Medical Officer, VentiRx PharmaceuticalsCertain immunomodulators target molecules that show marked differences between species. The HumanMAP v1.6 panel of biomarkers (Myriad RBM) provided a link between non-human primates and human clinical development of VTX-2337—a novel small molecule targeting Toll-like receptor 8 (TLR8).

10:20 Coffee Break

11:00 T-Cell Immunotherapy at UPenn: An Integrated Academic Translational Model for Success

Michael Kalos, Ph.D., Director, Translational and Correlative Studies Laboratory, University of Pennsylvania School of Medicine

We will discuss infrastructure elements whose implementation has been crucial for the successful establishment of the T-cell Immunotherapy program, and discuss specific examples of the successful translation of novel therapies from the bench to the bedside. 

11:30 Collaboration in Translational Science: Leveraging the Best of Both Worlds

Moderator: Patricia McDonald, Ph.D., Associate Scientific Director, Translational Research, The Scripps Research Institute

Open discussion focused on the academic-industry collaboration, identification of niche expertise within an academic organization, cultural differences of pharma and academic and how to work within changing timelines/resources/personnel. Audience participation is encouraged.

12:00 pm Presentation to be Announced

12:30 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own



1:45 Chairperson's Remarks

Rong Chen, Ph.D., Scientist, Bioinformatics, Pediatrics & Systems Medicine, Stanford University

1:50 Talk Title to be Announced

Rong Chen, Ph.D., Scientist, Bioinformatics, Pediatrics & Systems Medicine, Stanford University

2:20 Building a Translational Informatics Infrastructure Organically

Shoibal Datta, Ph.D., Associate Director, R&D Information Technology, Therapeutic Areas & Translational Medicine, Biogen Idec, Inc.

Translational data sets by their very nature involve the need to meaningfully integrate data from multiple traditional silos within R&D, each with complex and often heterogeneous data representations. This often makes it difficult to implement an informatics infrastructure for this space. Biogen Idec’s experience with this problem will be shared and a case study of how an infrastructure was developed will be presented.

2:50 Implementation of Translational Research Informatics Platform at City of Hope

Ajay Shah, Ph.D., Director, Research Informatics, City of Hope

3:20 Close of Conference

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