Molecular Medicine Tri-Conference 2014 Poster Presenters
Andre Hass; Astrid Ammendola; Roland Baumgartner; Daniel Vitt; and Thomas Herz: Driving the Biomarker Rational: A Fully Integrated Translational Pharmacology Concept for Focused Drug Development
Yasushi Noguchi; Akira Imaizumi; Atsuko Shinhara; Hiroshi Yamamoto; Hiroo Yoshida; Shunji Takehana; Nobuhisa Shimba; Maiko Mori; and Nastumi Nishikata: A Blood-Based Amino Acid Biomarker Panel for Aid in Early Detection of Cancer
Andreas Hanne; Lisa Heinrich; Peter Scheinert; and Guido Krupp: Applications of Synthetic mRNAs and GMP-Compliant Production Requirements: (1) Generation of Highly Efficient and Highly Specific Vaccines with Therapeutic Uses (2) Highly Modified Synthetic mRNAs for Cellular Reprogramming
Andreas Hanne; Lisa Heinrich; Peter Scheinert; Kai Pohlmeier; and Guido Krupp: Full Range of GMP-Compliant Synthetic Nucleic Acids
Susanne Quabius; Rolf Jaggi; and Guido Krupp: High Quality FFPE RNA from Challenging Samples for Digital Multiplex Quantification
Seungjin Lee; Kiseok Kim; Sungho Ryu; Dongil Han; and Jongha Jung: Efficient Isolation and Elution of Cancer Cells with Aptamer
Beth Israel Deaconess Medical Center
Sharon Fox; Charles Law; and Beverly Faulkner-Jones: Pathologist Gaze Pattern in the Evaluation of Specimen Presentation on Digital Platforms
Kashef Qaadri and Christian Olsen: Geneious R7: A Bioinformatics Platform for Biologists
Gregory D. Lyng; Stephen T. Sonis; and Maria L. Mancini: Modeling the Differential Responses of Cancer Stem Cells (CSCs) as Heterogeneous Versus Homogenous Populations in Human Cancers
Bioprocessing Technology Institute, A*STAR
Ruiyang Zou; Heng-Phon Too; and Lihan Zhou: A Novel and High Performance qPCR Assay Platform for Circulating MicroRNA Biomarker Discovery
Lihan Zhou; Jimmy So; Feng Zhu; Wei-Peng Yong; Yik Ying Teo; Celestial Yap; Koji Kono; Kee Seng Chia; Khay-Guan Yeoh; Heng-Phon Too; and Ruiyang Zou: Identification of Serum miRNA Biomarker for Early Detection of Gastric Cancer
BioStorage Technologies, Inc.
Kristina Robson and Scott Kaiser: Smartsourcing Strategies for Creating Sustainable Biospecimen Resources in Medical Research
Canterbury Health Laboratories
Kit Doudney; Peter George; and Hannah Kennedy: A First Foray into the Development and Implementation of Exome Sequencing in a Clinical Diagnostic Setting
Chang-Gung Memorial Hospital at Linkou
Shu-Jen Chen; Chia-Chun Chen; Yu-Sun Chang; Err-Cheng Chan; Jinn-Shiun Chen; and Pi-Yueh Chang: Evaluate CRC-Related MicroRNA Expression Pattern in Plasma and Stool Samples from CRC Patients
Andras Stracz and Krisztián Niesz: A Flexible Library Design Platform to Conduct Innovative Chemistry
Masami Fujiki and Krisztián Niesz: CRAIS Checker: A Simple Compliance Tool That Helps You to Stay on the Safe Side
Lisa K. Jennings and Jayaprakash Kotha: Standardization of Flow Cytometry Methods for Platelet Surface Receptor Quantification in Clinical Studies
Clearbridge Biomedics Pte. Ltd.
Chwee Teck Lim and Ali Asgar S. Bhagat: Label-Free Circulating Tumor Cells Enrichment Using Inertial Microfluidics
Commonwealth Scientific and Industrial Research Organisation (CSIRO)
Susan M. Mitchell; Horace R. Drew; Thu Ho; Glenn S. Brown; Neil F. W. Saunders; Konsta R. Duesing; Michael J. Buckley; Rob Dunne; Iain Beeston; Keith N. Rand; Aidan McEvoy; Melissa L. Thomas; Rohan T. Baker; David A. Wattchow; Graeme P. Young; Trevor J. Lockett; Susanne K. Pedersen; Lawrence C. LaPointe; Peter L. Molloy; and Jason P. Ross: Colorectal Cancer Methylation Biomarkers
Susan M. Mitchell; Peter L. Molloy; Keith N. Rand; and Jason P. Ross: Helper-Dependent Chain Reaction (HDCR), a Unique PCR Method with Sensitivity and Specificity Suitable for DNA Diagnostic Assays
Edwin Rudd; Austin Purdy; James Han; Srikanth Kakumanu; Adrian Palmer; Guillaume Durin; Jim Laugharn; and Hamid Khoja: Active Deparaffinization Drives Improved Workflow and Superior Data Quality for FFPE Tissue Nucleic Acid Extraction
Victor Koong; Yuko Williams; Alex Ko; and Don Weldon: miRNA’s Used as Cancer Biomarkers to Enrich from Mixed Populations of Live Epithelial and Mesenchymal Cells Show Positive Correlation with Cellular Invasion
Ann Meyer; Jessica Alexander; Jessica Xu; Liying Yan; and Matthew Poulin: Methylation, Copy Number, and LOH Analysis of Chr8q24 for Discovery of Ovarian and Breast Cancer Biomarkers
Faculdade de Ciências e Tecnologia
Sara Figueiredo; Pedro Pedrosa; Carla Clemente; Wolfgang Fritzsche; John Greenman; Steve Haswell; and Pedro Viana Baptista: Gold Nanoprobes for EGFR Mutation Characterization Directly from Cells
Daniel V. Luís; Joana Silva; Ana Isabel Tomaz; Rodrigo F.M. de Almeida; Daniela Rosa; Miguel Larguinho; Luísa M.D.R.S. Martins; Telma F.S. Silva; Armando J.L. Pombeiro; Pedro V. Baptista; and Alexandra R. Fernandes: Anti-Proliferative Potential of a Co(II) Coordination Compound Bearing 1,10-Phenanthroline-5,6-Dione: DNA and Protein Interaction Studies and Its Application in Cancer Therapy
Theo Oliveira; Alexandre Pereira; Miguel Mitne-Neto; and Louise Teixeira Cerdeira: Efficient and Accurate Pipeline for Diagnosis of Hypertrophic Cardiomyopathy by Next-Generation Semiconductor Sequencing
Flávio Mavignier Carcano; Bruno Feres de Souza; Ramon de Oliveira Vidal; Cristovam Scapulatempo Neto; Cristiano Ribeiro Viana; Louise Teixeira Cerdeira; André Lopes Carvalho; and Marcos Tadeu dos Santos: Cancer of Unknown Primary Origin: A Gene Expression Profiling Test for the Right Classification
Maria Wendt; Peter Ernst; Christopher Smith; Hans Peter Fischer; and Mark Aquino: Genedata Biologics – An Integrated Data Management Platform for Biopharmaceutical R&D
Maria Wendt; Peter Ernst; Christopher Smith; Hans Peter Fischer; and Kurt Zingler: New Tools for High-Throughput Engineering, Cloning and Expression of Multispecific Next-Generation Antibodies
Wei Min; M. Sue-Ann Woo; Ruqin Kou; Jessica Bellifemine; Shihong Li; Yanshan Niu; Guanghui Hu; and Yun Liang: Personalized Medicine: The Next Generation
Genome Institute of Singapore
Joyce An-Yi Tai; Edwin Kok-Hao Lim; Majid Ebrahimi Warkiani; Daniel Shao-Weng Tan; Chwee-Teck Lim; Robson Paul; Hillmer Axel; Bing Lim; and Say-Li Kong: The Genomics Profiling of Lung Cancer Circulating Tumor Cells Enumerated with Spiral Microchannel
Gen-Probe Life Sciences Ltd.
Leigh Demain; Paul Docherty; Michael Kaiser; David Reed; David Scott; and Robert James Holt: A Comparison of the Invader® and InvaderPLUS® Platforms with Other Genotyping Technologies
KeeSoo Nam; Sunhwa Oh; Juyeon Lim; SeungAh Yoo; Incheol Shin; and Kyung-Min Lee: ECM1 Regulates Cell Proliferation and Trastuzumab Resistance Through Enhancement of EGF-Signaling
Kyung-Min Lee; KeeSoo Nam; Sunhwa Oh; SeungAh Yoo; Incheol Shin; and Juyeon Lim: CD24 Regulates EMT and CSC Properties Through Modulation of Notch1 Expression via a p38MAPK-Dependent Mechanism
SeungAh Yoo; Kyung-Min Lee; Sunhwa Oh; Juyeon Lim; Incheol Shin; and KeeSoo Nam: Ablation of CD44 Decreases Cell Proliferation, Migration and Invasion via Down-Regulation of c-Src Transcription
KeeSoo Nam; SeungAh Yoo; Kyung-Min Lee; Juyeon Lim; Incheol Shin; and Sunhwa Oh: EGFR Negates Exogenous HER2 Effect in MDA-MB-231 Cells
Horizon Discovery Limited
Chris Thorne; Vicky Spivey; Amy Mulligan; Jonathan Frampton; John Goodall; Paul Morrill; and Karin Schmitt: Design and Validation of Multiplex Reference Standards for Mutation Profiling on NGS Platforms
Shen L. Wei; Vicky Spivey; John Goodall; Jonathan Frampton; Paul Morrill; and Karin Schmitt: Design, Validation and Application of FISH Reference Slides for Oncology Assay Development and FISH Probe Evaluation
Industrial Technology Research Institute
Su-Jan Lee; Chi-Kuan Chen; Johan Chien; Yuan-Chung Kao; Chien-An Chen; Pei-Shin Jiang; Ting-Shou Chen; and Jane SC Tsai: Novel Mutation Enrichment Detection Method for Epidermal Growth Factor Receptor (EGFR)
Instituto Superior Tecnico
Filipe Cardoso; Sofia Martins; Jorge Gaspar; Susana Cardoso; Gabriel Monteiro; Paulo Freitas; and Tomas Dias†: Towards the Implementation of a Portable Magnetoresistive Point-of-Care System for Cell-Free DNA Detection in Cancer Diagnosis
Jonathan Dudley; Katie Beire; Derek Anderson; Kristin Smith; Guoli Chen; Christopher D. Gocke; James R. Eshleman; Ming-Tseh Lin; and Grzegorz T. Gurda: Tumor Cellularity as a Quality Assurance (QA) Measure for Accurate Clinical Detection of BRAF Mutations in Melanoma
Katholieke Universiteit Leuven
Jiqiu Cheng; Ligia Mateiu; Masoud Zamani Esteki; Parveen Kumar; Eftychia Dimitriadou; Evelyne Vanneste; Yves Moreau; Joris Vermeesch; Thierry Voet; and Niels Van der Aa: Genome-Wide Copy Number Profiling of Single Cells in S-Phase Reveals DNA-Replication Domains
Mokang Mouanoutoua; Christopher Trinh; Dora Gutierrez; Jonathan Wang; and Priscilla Yim: General Purpose Reagents for Clinical Molecular Diagnostics by PCR
Shiaw-Min Chen; Mark E. Shannon; Tom Xu; Junko Stevens; and Mousumi Rath: An Improved Sample-to-Sequence Workflow for Fast and Robust miRNA Analysis on the Ion Torrent PGM Using the TaqMan® miRNA ABC Purification Kit
Medical Prognosis Institute, Inc.
Anker Hansen; Jon Askaa; Peter Buhl Jensen; and Steen Knudsen: A Biomarker That Can Predict Which Indication Will Be Approved by the FDA
Medical University of Vienna
Paul Speiser; Nina Pecha; Eva Schuster; Michael Novy; Reinhard Horvat; Isaac Kinde; Yuxuan Wang; Luis Diaz; Kenneth W. Kinzler; Nickolas Papadopoulos; Bert Vogelstein; Robert Zeillinger; and Elisabeth Maritschnegg†: The ALPINE Technique: Molecular Detection of Ovarian Cancer, a Proof of Concept Study
National Dong Hwa University
Max K. Leong: In Silico Prediction of Promiscuous Breast Cancer Resistance Protein Inhibition
National Health Research Institutes
Chi-Ling Chen; Tseng-Chang Yen; Pei-Jer Chen; Yun-Fan Liaw; and Shiu-Feng Huang: Introduction of Taiwan Liver Cancer Network
National Science and Technology Development Agency
Suchintana Chumseng; Tararaj Dharakul; and Deanpen Japrung: Selection and Characterization of Aptamers for the Detection of Diabetes Mellitus
Warangkana Chantima; Charin Thepthai; Tararaj Dharakul; and Satita Tapaneeyakorn: Characterization of a Novel Monoclonal Antibody Raised Against an N-Terminal Peptide of Human Mig7
National Tsing Hua University
Ian C. Hsu: Using UVB Small Perturbation to Study the Biological Steady State
National University Health System
Te Chih Liu; Evelyn Siew Chuan Koay; and Kok Siong Poon: Comparison of Three Laboratory-Developed Tests for Detection of the MYD88 L265P Mutation in Differential Diagnosis of Waldenstrom Macroglobulinemia
Lily Chiu; Evelyn Siew Chuan Koay; and Kok Siong Poon: In-House Sequence Analysis of the GCK, HNF1A and HNF4A Genes for Diagnosis Confirmation of MODY: Identification of Two Novel Mutations
National University of Ireland
Ciara Mullen; Louise O’Connor; Evelyn Keady; Sinead Lahiff; Barry Glynn; and Terry Smith: Development and Clinical Evaluation of a Real-Time LAMP Assay for the Detection of Group B Streptococcus in Pregnant Women
National University of Singapore
Seok-Hwee Koo; Paul Chui; Chee Seng Ku; Yudi Pawitan; Edmund J. D. Lee; and Elsa Haniffah Mejia-Mohamed†: Whole Exome Sequencing Approach to Identify Genetic Variants Causing Sudden Unexplained Death Syndrome
Lim Kok Hao Edwin; Jianzhu Chen; Lim Bing; and Monireh Soroush Noghabi†: Identifying and Characterizing Lung Cancer Tumor Initiating Cells Using Single Cell Analysis
Lorcan Sherry; Mark Anderson; John Waller; and Pauline McEwan: Quantification of Drug Response and Biomarker Parameters Within the Tumor Microenvironment Using Whole Slide Digital Image Analysis
Bangzhong Lin; Yoon-Jeong Kim; Tomona Yamaguchi; Takayuki Fujieda; Takaharu Yagi; Yoshitaka Kondo; Keizo Miyata; Fuminori Kato; Yasufumi Kaneda; and Kazuto Nunomura: High-Throughput Screening of siRNA Library Using Automatic Dispenser System
Joshua E. Allen; David T. Dicker; Wafik S. El-Deiry; and Varun Vijay Prabhu†: Small Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem Cells In Vitro and In Vivo
Alexandra Vamvakidou; Seungtaek Lee; and Vanessa Braunstein: AlphaLISA Technology and the SciSTREAM Add-On for Spotfire Provide a Quick Analysis of Various Analytical Assays
Claire Adam; Garry Farnham; Laura Chegwidden; Janusz Jankowski; and Xinzhong Li: Pathway Analysis of Barrett’s Oesophagus Genome Wide Association Study
Postgraduate Institute of Medical Education and Research
Jyotdeep Kaur; Rashmi Bagga; and Beenish Rahat†: Temporal Expression and Promoter Region Methylation of c-Myc During Normal and Pathological Pregnancies
Precision Bioservices, Inc.
Rotimi Awoyode; Anna Le; Erika Shepherd; Tai Osunsan; Erik Neidinger; Katheryn Shea; Michael Waddington; and Faith Bahunde: Validation and Standardization of an Efficient Stabilization Method for Transport of PBMC to a Central Laboratory for RNA Extraction
Rod Pennington; Doug Storts; and Terri McDonnell: Considerations for Use of Taq Polymerase in Molecular Diagnostic Assays
PROOF Centre of Excellence
Zsuzsanna Hollander; Karen Lam; Sara Assadian; Darlene Dai; Casey Shannon; Virginia Chen; Gabriela Cohen Freue; Scott Tebbutt; Robert Balshaw; Christoph Borchers; Ross Davies; Diego Delgado; Haissam Haddad; Andrew Ignaszewski; Debra Isaac; Daniel Kim; Alice Mui; Miroslav Rajda; Lori West; Michel White; Shelley Zieroth; Robert McMaster; Paul Keown; Raymond Ng; Bruce McManus; and Janet Wilson-McManus: Blood Test to Monitor for the Absence of Acute Cardiac Rejection
Scott Tebbutt; Raymond Ng; David Brener; Karen Lam; Zsuzsanna Hollander; Casey Shannon; Virginia Chen; Darlene Dai; Sara Assadian; Jolina Carson; Breanne Crouch; Marek Zarzycki; George Mak; Bruce McManus; and Janet Wilson-McManus: Harnessing an “Omics” Pipeline to Produce High Value Blood Tests
Provista Diagnostics, Inc.
Meredith C. Henderson; Susan Yeh; Sherri Borman; Alan Hollingsworth; and David E. Reese: Serum Biomarker Concentrations in Benign Breast Conditions and Ductal Carcinoma In Situ: Designing a Diagnostic Biomarker Panel That Can Distinguish Between Benign Conditions and Invasive Breast Cancer
Punjabi University, Patiala
Devinder S. Sandhu and Shruti Caplash†: Association of GST Gene Polymorphism with Susceptibility to Leukemia in Punjabi Population and Differential Chemotherapy Response
Praveen Balgir and Harsimran Kaur†: Pharmacogenomics of Hypertension Among Punjabi Population
Ray Ahmed: Automated Large-Volume Extraction of Circulating, Cell-Free DNA Using the QIAsymphony SP Instrument
RainDance Technologies, Inc.
Leonora Balaj; Ben Ho Park; Saumya Das; Manuel Krispin; Valerie Taly; and Michael Samuels: Quantitative Nucleic Acid Analysis Using Digital PCR: Absolute Counting of DNA (Examples Including Liquid Biopsies in Cancer) and RNA (mRNA and miRNA Using One-Step RT-dPCR)
RiboMed Biotechnologies, Inc.
David McCarthy; Walter Pulverer; Andreas Weinhausel; and Michelle Hanna*: GliomaSTRAT™: A Four Gene DNA Methylation Based Laboratory Developed Test for Glioma Stratification by Tumor Aggressiveness and Potential Drug Response
Ricardo Coletta; Carlos Curti; Andréia Leopoldino; and Lays Martin Sobral: SET/I2PP2A Overexpression in a Normal Oral Keratinocyte (NOK-SI) Cell Lineage Induces Cell Transformation with Tumorigenic Phenotype
Sung-Il Ko; Na-Hyun Kim; Won-Jun Oh; Hae-Joon Park; and Sun-Hyung Kim: Evaluation of the AnyplexTMII HSV-1/2 Assay for the Detection and Typing of Herpes Simplex Virus-1 and 2
Min-Jung Kwon; Hee-Yeon Woo; Soon-Young Paik; and Yun-Jee Kim: Prevalence of Human Papillomavirus Infection and Genotype Distribution Determined by the Cyclic-Catcher Melting Temperature Analysis in Korean Medical Checkup Population
S. Teixeira; S. Salgado-Pires; Z. Johnson; M. Deehan; W. Ferlin; F. Guilhot; A. Lu; and Lynn Zieske*: Use of the Erenna® Immunoassay Platform to Detect Pro-Inflammatory Cytokines in an In Vitro Cytokine Release Assay
Lidia C. Sambucetti: Methods for Enumeration and Analysis of Single Circulating Tumor Cells (CTCs)
Sonya Youngju Park and Jinyoung Yoo: Assessment of Immunohistochemistry with EGFR Mutation-Specific Antibodies in Pulmonary Adenocarcinoma
Christopher Earhart; Casey Hughes; Dawson Wong; Robert Wilson; Raj Rohatgi; Shan Wang; and Chin Chun Ooi†: Optimization of a Microfabricated Magnetic Sifter for Cell Capture and Isolation
Wenyi Wang; Aung-Kyaw Chi; Yu Fan; Ronald W. Davis; Curt Scharfe; and Peidong Shen: Multiplex Target Capture with Double-Stranded DNA Probes for Clinical Sequencing
Christopher Earhart; Casey Hughes; Richard Gaster; Chin Chun Ooi; Robert Wilson; Lisa Zhou; Eric Humke; Lingyun Xu; Stephen Willingham; Erich Schwartz; Irving Weissman; Stefanie Jeffrey; Joel Neal; Rajat Rohatgi; Heather Wakelee; Shan Wang; and Dawson Wong†: Isolation and Mutational Analysis of Circulating Tumor Cells from Lung Cancer Patients with Magnetic Sifters and Biochips
Filip Janku; Ben Legendre; Gerald S. Falchook; Aung Naing; Veronica R. Holley; Siqing Fu; David S. Hong; Sarina A. Piha-Paul; Jennifer J. Wheler; Ralph G. Zinner; Vivek Subbiah; Apostolia M. Tsimberidou; Daniel D. Karp; Vanda M. Stepanek; Goran Cabrilo; Rajyalakshmi Luthra; Funda Meric-Bernstam; Agop Y. Bedikian; Bryan K. Kee; Cathy Eng; Michael J. Overman; Kevin B. Kim; Amy Kruempel; Jaclyn Pope; Courtney Cubrich; Grant Wu; Yanggu Shi; Vlada Melnikova; Marcia Lewis; Razelle Kurzrock; and Katherine Richardson: Utility of ICE COLD-PCR Coupled to Sanger Sequencing or Next Generation Sequencing for Increased Mutation Detection Sensitivity During Patient Monitoring from Circulating Free DNA
TriLink BioTechnologies, Inc.
Natasha Paul; Sabrina Shore; Michelle Salcedo; and Gerald Zon: Improved Small RNA Library Preparation Workflows for Next Generation Sequencing
Sabrina Shore; Natasha Paul; Richard Hogrefe; Alexandre Lebedev; and Gerald Zon: Pushing the Limits of PCR, qPCR and RT-PCR Using Hot Start dNTPs
Universitas Padjadjaran, Bandung
Ani Melani Maskoen; Edhyana Sahiratmadja; Ratu Safitri; Supartini Syarif; Herman Susanto; and Fitri Rahmi Fadhilah†: Phylogenetic Study of L1 Protein Human Papillomavirus Type 16 from Cervical Cancer Patients in Bandung
Xiaoxi Wei; Mark Kline; Bing Gong; and Guizella Rocabado†: Macrocycles Designed to Form Self-Assembling, Synthetic Nanopores with Cationic Selectivity
University of California, Irvine
Dong-Ku Kang; Weian Zhao; and Kaixiang Zhang†: Rapid, Circulating Tumor Cell Detection from Blood Using Microencapsulated System
University of California, Los Angeles
Pam Ting; John Colicelli; and Abinav Baweja†: Outflanking BCR-ABL1 Drug Resistance
University of California, San Diego
Suping Zhang; Christina C. N. Wu; Grace Liu; Liguang Chen; Fitzgerald Lao; Jian Yu; Laura Rassenti; Michael Y. Choi; Stephen B. Howell; Malcolm Finlayson; Thomas J. Kipps; and Hsien Lai†: Selective Cytotoxicity of A6 Peptide Against ZAP-70 Expressing CLL B-Cells
Dana W. Y. Tsui; Sarah-Jane Dawson; Tim Forshew; Davina Gale; Francesco Marass; Anna M. Piskorz; Christine Parkinson; Tan Min Chin; James D. Brenton; Carlos Caldas; Nitzan Rosenfeld; and Muhammed Murtaza†: Investigating Genomic Evolution and Acquired Resistance in Solid Cancers by Sequencing Plasma DNA
Adam Marsh; Jeb Connor; and Annamarie Pasqualone†: GenPro: Epigenetic Profiling of CpG DNA Methylation Sites
University of Medicine and Pharmacy Iuliu Hatieganu
Valentina Pileczki; Roxana Cojocneanu Petric; Laura Pop; Cornelia Braicu; and Ioana Berindan Neagoe: TNF siRNA as Modulators of Apoptosis and Angiogenesis, in Cell Migration and Invasion in Triple Negative Breast Cancer Cells (TNBC)
Christopher Mader; Amar Koleti; Hande Küçük; Samindaa Abeyruwan; Uma Vempati; Nakul Datar; Shivani Aradhye; Ricardo Pissano; Ubbo Visser; Stephan Schürer; and Caty Chung: The Library of Integrated Network-Based Cellular Signatures (LINCS) Information FramEwork (LIFE)
University of New South Wales
B. Balakrishnar; N. Kienzle; P. de Souza; and Therese Becker: Efficient Immunomagnetic Isolation of Melanoma Cells with Diverse Genetic Backgrounds from Blood
University of North Carolina
Hendrik DeJong; Alex B. Lopez; and Patricia Basta: Optimized Method for DNA Extraction from Saliva and Other Non-Blood Sources
Kar Ming Fung and Lewis A. Hassell: Five Years of Whole Slide Imaging (WSI): Successes and Frustrations
Andelka M. Phillips†: Direct-to-Consumer Genetic Testing: A Legal Perspective
University of Tennessee, Memphis
Jin Wang; Jianjun Chen; Duane D. Miller; and Wei Li: Overcoming Acquired Resistance in BRAF[V600] Melanoma Using a Combination of ABI-274 and Vemurafenib in a Predictive A375RF21 Model
Jayaprakash Kotha and Lisa K. Jennings: The Vasodilator-Stimulated Phosphoprotein Assay as a Companion Test to Assess P2Y12 Receptor Activity in Clinical Studies
University of Wisconsin, Madison
Rashmi Agni; Dawn Albrecht; Jeff Bacher; Ian Grimes; Richard Halberg; Daiva Kanopiene; Doug Storts; Mark Reichelderfer; Kelly Richie; Chelsie Sievers; Jolanta Vidugiriene; Jennifer Weiss; and Ashley Anderson: New Markers for Improved Detection of MSI in Colon Polyps and Endometrial Cancers
Viator Technologies, Inc.
John Viator: Photoacoustic Detection and Automated Capture of Circulating Melanoma Cells
Victor Babeş University of Medicine and Pharmacy
Liana Gabriela Gruescu† and Andrada Camelia Guta†: Association of CYP2D6 and ADRB1 Single Nucleotide Polymorphisms and Response to Beta Blocker Therapy in a Patient Sample Set with Cardiovascular Diseases from Romania
Yonsei University Health System
Jinsil Seong; Yang-Gun Suh; Hyejung Cha; Seung-Hyun Yang; and Eun-Jung Lee: Matrix Metalloproteinase-2 and High Vascular Endothelial Growth Factor as Prognostic Markers for Intrahepatic Tumor Recurrence in Hepatocellular Carcinoma Patients Receiving Radiotherapy
Molecular Medicine Tri-Conference 2014 Symposia Poster Presenters
Gregory D. Lyng; Stephen T. Sonis; and Maria L. Mancini: Modeling the Differential Responses of Cancer Stem Cells (CSCs) as Heterogeneous Versus Homogenous Populations in Human Cancers
Victor Koong; Yuko Williams; Alex Ko; and Don Weldon: miRNA’s Used as Cancer Biomarkers to Enrich from Mixed Populations of Live Epithelial and Mesenchymal Cells Show Positive Correlation with Cellular Invasion
Massachusetts Institute of Technology
William G. Thilly and Elena Gostjeva: How to Kill Cancer Stem Cells Without Killing Normal Stem Cells in Adult Patients
National University of Singapore
Lim Kok Hao Edwin; Jianzhu Chen; Lim Bing; and Monireh Soroush Noghabi†: Identifying and Characterizing Lung Cancer Tumor Initiating Cells Using Single Cell Analysis
Koshua E. Allen; David T. Dicker; Wafik S. El-Deiry; and Varun Vijay Prabhu†: Small Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem Cells In Vitro and In Vivo
Istvan Szasz; Laura Vízkeleti; Szilvia Ecsedi; Viktória Koroknai; Tímea Kiss; Róza Ádány; and Margit Balazs: Resistance to BRAF Inhibitor PLX-4720 Resulting in Dramatic EGFR Gene Expression Changes in BRAFV600E-Positive Melanoma Cell Lines
Diagnostics For All, Inc.
Sidhartha Jain; Matthew Stewart; Jeremy Schonhorn; Shailendra Kumar; Jason Rolland; and Erin Coonahan: Diagnostics For All: Rapid, Paper-Based, Low-Cost Diagnostic Tests for Resource-Limited Settings
Industrial Technology Research Institute
Chi-Han Chiou; Chih-Jen Chen; Hsiang-Yuan Huang; Chih-Hsiu Yin; Yu-Ying Lin; Shao-Hsing Yeh; Cheng-Tai Chen; Pei-Yu Peng; Jing-Tsyr Lin; Wen-Ting Chiang; Ting-Shou Chen; and Jane SC Tsai: A Novel Magnetic Droplet-Based Immunoassay System for Point-of-Care Testing
National Science and Technology Development Agency
Suchintana Chumseng; Tararaj Dharakul; and Deanpen Japrung: Selection and Characterization of Aptamers for the Detection of Diabetes Mellitus
National University of Ireland
Ciara Mullen; Louise O’Connor; Evelyn Keady; Sinead Lahiff; Barry Glynn; and Terry Smith: Development and Clinical Evaluation of a Real-Time LAMP Assay for the Detection of Group B Streptococcus in Pregnant Women
TriLink BioTechnologies, Inc.
Natasha Paul; Sabrina Shore; Michelle Salcedo; and Gerald Zon: Improved Small RNA Library Preparation Workflows for Next Generation Sequencing
Sabrina Shore; Natasha Paul; Richard Hogrefe; Alexandre Lebedev; and Gerald Zon: Pushing the Limits of PCR, qPCR and RT-PCR Using Hot Start dNTPs
University of Science and Technology
Min-Jung Kang and Hyojeong Han: Discovery and Validation of Substance P and Neuropeptide Y as Potential Biomarkers for Diagnosis of Acute Myocardial Infarction
University of Tennessee, Memphis
Jayaprakash Kotha and Lisa K. Jennings: The Vasodilator-Stimulated Phosphoprotein Assay as a Companion Test to Assess P2Y12 Receptor Activity in Clinical Studies
Andre Hass; Astrid Ammendola; Roland Baumgartner; Daniel Vitt; and Thomas Herz: Driving the Biomarker Rational: A Fully Integrated Translational Pharmacology Concept for Focused Drug Development
Canterbury Health Laboratories
Kit Doudney; Peter George; and Hannah Kennedy: A First Foray into the Development and Implementation of Exome Sequencing in a Clinical Diagnostic Setting
Theo Oliveira; Alexandre Pereira; Miguel Mitne-Neto; and Louise Teixeira Cerdeira: Efficient and Accurate Pipeline for Diagnosis of Hypertrophic Cardiomyopathy by Next-Generation Semiconductor Sequencing
Flávio Mavignier Carcano; Bruno Feres de Souza; Ramon de Oliveira Vidal; Cristovam Scapulatempo Neto; Cristiano Ribeiro Viana; Louise Teixeira Cerdeira; André Lopes Carvalho; and Marcos Tadeu dos Santos: Cancer of Unknown Primary Origin: A Gene Expression Profiling Test for the Right Classification
Mokang Mouanoutoua; Christopher Trinh; Dora Gutierrez; Jonathan Wang; and Priscilla Yim: General Purpose Reagents for Clinical Molecular Diagnostics by PCR
National University of Singapore
Seok-Hwee Koo; Paul Chui; Chee Seng Ku; Yudi Pawitan; Edmund J. D. Lee; and Elsa Haniffah Mejia-Mohamed†: Whole Exome Sequencing Approach to Identify Genetic Variants Causing Sudden Unexplained Death Syndrome
Adam Marsh; Jeb Connor; and Annamarie Pasqualone†: GenPro: Epigenetic Profiling of CpG DNA Methylation Sites
University of Wisconsin, Madison
Rashmi Agni; Dawn Albrecht; Jeff Bacher; Ian Grimes; Richard Halberg; Daiva Kanopiene; Doug Storts; Mark Reichelderfer; Kelly Richie; Chelsie Sievers; Jolanta Vidugiriene; Jennifer Weiss; and Ashley Anderson: New Markers for Improved Detection of MSI in Colon Polyps and Endometrial Cancers
PROOF Centre of Excellence
Scott Tebbutt; Raymond Ng; David Brener; Karen Lam; Zsuzsanna Hollander; Casey Shannon; Virginia Chen; Darlene Dai; Sara Assadian; Jolina Carson; Breanne Crouch; Marek Zarzycki; George Mak; Bruce McManus; and Janet Wilson-McManus: Harnessing an “Omics” Pipeline to Produce High Value Blood Tests
Zsuzsanna Hollander; Karen Lam; Sara Assadian; Darlene Dai; Casey Shannon; Virginia Chen; Gabriela Cohen Freue; Scott Tebbutt; Robert Balshaw; Christoph Borchers; Ross Davies; Diego Delgado; Haissam Haddad; Andrew Ignaszewski; Debra Isaac; Daniel Kim; Alice Mui; Miroslav Rajda; Lori West; Michel White; Shelley Zieroth; Robert McMaster; Paul Keown; Raymond Ng; Bruce McManus; and Janet Wilson-McManus: Blood Test to Monitor for the Absence of Acute Cardiac Rejection
Provista Diagnostics, Inc.
Meredith C. Henderson; Susan Yeh; Sherri Borman; Alan Hollingsworth; and David E. Reese: Serum Biomarker Concentrations in Benign Breast Conditions and Ductal Carcinoma In Situ: Designing a Diagnostic Biomarker Panel That Can Distinguish Between Benign Conditions and Invasive Breast Cancer
Instituto Superior Tecnico
Filipe Cardoso; Sofia Martins; Jorge Gaspar; Susana Cardoso; Gabriel Monteiro; Paulo Freitas; and Tomas Dias†: Towards the Implementation of a Portable Magnetoresistive Point-of-Care System for Cell-Free DNA Detection in Cancer Diagnosis
RainDance Technologies, Inc.
Leonora Balaj; Ben Ho Park; Saumya Das; Manuel Krispin; Valerie Taly; and Michael Samuels: Quantitative Nucleic Acid Analysis Using Digital PCR: Absolute Counting of DNA (Examples Including Liquid Biopsies in Cancer) and RNA (mRNA and miRNA Using One-Step RT-dPCR)
Dana W. Y. Tsui; Sarah-Jane Dawson; Tim Forshew; Davina Gale; Francesco Marass; Anna M. Piskorz; Christine Parkinson; Tan Min Chin; James D. Brenton; Carlos Caldas; Nitzan Rosenfeld; and Muhammed Murtaza†: Investigating Genomic Evolution and Acquired Resistance in Solid Cancers by Sequencing Plasma DNA
Seoul National University Bundang Hospital
Eun-Ju Choi; Francis SG Nahm; and Pyung Bok Lee: Cerebral Protein Change in the Rat Chronic Post-Ischemic Pain Model